Sex linked deafness: Wilde revisited.
نویسنده
چکیده
Sex linked recessive deafness is a rare cause of male genetic deafness, estimated to account for 6.2% of male genetic deafness in 1966. A male excess was found in the deaf population of Ireland in 1851. Reevaluation of this survey of 1851 confirms sex linked deafness as a factor in the disproportionate number of deaf males and suggests that 5% of congenital male deafness was the result of sex linked recessive deafness. This study confirms that a small but constant proportion of male deafness is the result of sex linked recessive deafness. The figure derived is used to calculate an empirical risk for carrier status in female sibs of isolated cases of male deafness.
منابع مشابه
Hearing impairment in female carriers of the sex-linked syndrome of deafness with albinism.
A family which is part of a large kindred in which a sex-linked recessive syndrome manifested by profound deafness and partial albinism was reported by Margolis (1962) and independently by Ziprkowski et al. (1962). According to their reports hearing impairment was not found in carriers. The family first came to our attention because of deafness of a male child (III.5, Fig. 1) and later for gene...
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عنوان ژورنال:
- Journal of medical genetics
دوره 27 6 شماره
صفحات -
تاریخ انتشار 1990